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Preheat oven to 375 degrees. Line a baking sheet with parchment paper.
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Whisk together flours, sugar, baking powder and salt in a large bowl. Cut in butter with a pastry cutter or rub with fingers until the mixture has the texture of coarse meal. Add blueberries. Set aside.
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Whisk together buttermilk, egg and vanilla in small bowl. Drizzle over flour mixture
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and stir lightly with a fork until dough comes together and all but a small amount of the flour mixture comes together in a bowl. Add about another tablespoon of buttermilk, and turn out onto lightly floured surface. Gently knead dough once or twice just to incorporate flour into dough. Pat dough into a 1 inch round. Cut into 12 wedges. Transfer to prepared baking sheet. Bake until golden brown and cooked through, about 22 minutes. Let cool for about 10 minutes. Mix together glaze. Drizzle glaze onto scones. Serve immediately.